Anastrozole – a potent inhibitor of aromatase, selective non-steroidal drug is used in the sport for the prevention of gynecomastia and water retention in the body. Used only when long-term steroid treatment with high doses of drugs. One of the most popular and effective drugs for the prevention of side effects of feminization. It acts much better known Tamoxifen, as it is based on a different principle action.
This product is intended to inhibit aromatization and reduces its activity by 80-90% of the initial level. From the other drugs it is characterized by high efficiency and speed of action. Already after a couple of hours after the aromatization process is almost entirely blocked by the maximum concentration of the drug.
The operating principle of anastrozole is fundamentally different from the known Tamoxifen, which blocks estrogen alone, but not to interrupt the process of flavoring. This drug inhibits aromatization itself, hence, estrogens are not synthesized in the body and can not be produced. One-time application in a dose of 1 mg Anastrazole lowers estradiol levels in the blood of 80% in the first hours after administration.
The first products of this type have been developed almost simultaneously with tamoxifen in the 1980s in the United States. Since then, by 1995, there was a third-generation aromatase inhibitors, which concerns this tool and its analogs (Arimidex), and started selling them. In medicine they are used in malignant breast tumors, with high activity of estrogen receptors in the tumor tissue.
Designed to welcome postmenopausal women. Since many breast cancers are stimulated by estrogen, the drug is intended to reduce the amount of estrogen in the blood, thereby slowing the progression of the disease. Some experimental studies of estradiol levels in the blood and decreased to 98% of the initial concentration.
In bodybuilding, the active ingredient of the drug is used to prevent gynecomastia and fluid accumulation, side effects from taking testosterone esters and other drugs with androgenic activity. Recommended only for experienced and professional athletes, conducting courses with esters of testosterone, Sustanon or other medications with androgenic activity.
The cost of Anastrozole is totally justified, since a day is enough with just one pill. Acceptance begin with the start of the course or steroids, or when the first signs of flavoring 0.25 – 1 mg per day. Apply the drug on an empty stomach better because it is faster and more completely absorbed from the gastrointestinal tract into the circulatory system. Maximum concentration in blood reached at 2 hours after administration.
Anastrozole is the right approach for 10-14 days reduces the side effects of severe courses of steroids, in particular flavoring mixes strong drugs. The effectiveness of anti-estrogen and confirmed by numerous clinical trials, but in view of the strength of its impact it is recommended not to all.
It is advisable to use the drug under the supervision of an experienced specialist. The drug itself has progestogenic and androgenic activity on the secretion of hormones cortisol and aldosterone no effect, it does not require the introduction of corticosteroids during the course.
Anastrozole has a long half-life (40-50 hours), and, even in small doses, is effective in preventing feminization in athletes. Excreted primarily in the urine and bile. It has no effect on testosterone production. Taking the drug for more than 1 mg per day and for a long time is not recommended.
The main advantages Anastrozole
- Rapid suppression of aromatization
- The powerful inhibitory effect
- Inhibition of 50% of estrogen
- Increased levels of testosterone
- The lack of estrogenic activity
- Lack progestogenic activity
- High Absorption
- Non-steroidal drug
Beginners should not use this remedy. Tablets are designed for experienced athletes, after they have gone through a long cycle of taking anabolic steroids in high doses. Anastrozole is prescribed in two cases: before the course of steroids as a prophylactic with therapeutic dosages, and after the course, if side effects occur.
The duration of the reception cycle of this remedy should not exceed 14 days. During this time the drug manifests all its useful properties. Take tablets on an empty stomach and drink with plenty of water – so the active ingredient quickly came from the gastrointestinal tract into the circulatory system. This tool must be used on a strict schedule. One day you take, the second you rest. You can take the drug at any time of the day. Sufficient for good results, the dose is 250 μg once a couple of days. It has been proven that a dosage of 0.5 to 1 milligram is required to reduce the level of estradiol by 50%.
Reviews of anastrozole
For all the merits of the athletes are two major drawbacks of the drug. Reducing the side effects of estrogen they confirm all reviews Anastrozole, so its effectiveness is quite proved. But in the course of action of the active drug and inhibits the synthesis of “good” cholesterol, necessary for the cardiovascular system, it is the first flaw.
It becomes an alternative to tamoxifen. In combination with finasteride statements are advised to use the drug to minimize pobochek steroids are converted to dihydrotestosterone.
On condition that affects muscles only positive. Having studied the reviews of anastrozole, the second drawback it can be called a relatively high price. Use of the drug is justified in the case of prolonged or courses with high doses of steroids.
Even the co-administration of Tamoxifen and Proviron does not give the same effect as the drug. Therefore, a sufficiently high price is justified anastrozole efficacy of the drug. People with sensitivity to the drug may be some side effects: acne, nausea, headache, drowsiness, allergic reactions.
The price of high cost due to anastrozole reviews synthesis of the drug, and can often be higher than the price of steroids themselves, which, of course, not happy bodybuilders. But do not skimp on your health. Compare what is more profitable – the price of these tablets or multiple physician visits and conducting surgical operations in the fight against gynecomastia.