Recently, more and more “dirty” anabolic steroids are appearing on the black market for anabolic drugs. This is due to the spread and populizatsii power sports and breeding handicraft (home) drugs that are cooked right in the kitchen. All of these preps cause a series of side effects and an estrogen jump in the athlete’s body; to prevent this, you need to know how to take anastrozole on the course and after the course.
Anastrozole – all beloved drug antiestrogenic effects. The market is presented in tablet form, the first mentions appear in the year 95. Initially, the drug was used exclusively by doctors for the treatment of breast cancer, but after it began to take and bodybuilding.
Anastrozole is a very strong inhibitor, 1 mg of the active substance can reduce the estradiol content by 85%. Do not put in one row anastrozole and tamoxifen, the effect of their effects is completely different.
Antitumor, inhibits the synthesis of estrogen.
The tool is a powerful and highly selective non-steroidal aromatase blocker . In postmenopausal females, estradiol is produced by transformation in the tissues of the peripheral organs of androstenedione into estrone with the participation of the enzyme aromatase . Estrone turns into estradiol.
Lowering estradiol causes a therapeutic effect in women who suffer from malignant tumors of the breast. In postmenopause, the use of 1 mg of anastrozole per day leads to a decrease in the estradiol content by 80%.
Rapid absorption of the drug, the highest concentration in the blood is reached after two hours when taken on an empty stomach. The half-life reaches 50 hours. Food slows down the speed of absorption.
Associated with blood proteins by 40%. Metabolized extensively. It is excreted by the kidneys in its original form 72 hours after ingestion. Metabolites are also excreted mainly by the kidneys.
Effects of taking anastrozole
- Effective suppression of aromatization;
- Powerful antiestrogen;
- Strong blocker;
- Able to bring down the level of estradiol concentration directly on the course for 2 hours;
- Displays and does not allow to retain water.
How to take
In bodybuilding taking anastrozole on the course should be no more than 2 weeks. Reception begins immediately, as the first signs of increased aromatization were found. For athletes with a low level of estradiol in the blood, 0.25 mg of active ingredient every other day is enough (this is a quarter tablet).
If something went wrong and the level of estrogen goes off 1.5-2 times, carry out prevention of 1 tablet every other day for two weeks. At the end, be sure to cancel the drug and check the level of estradiol. Note that there is no difference in the course or after the course you will take the drug.
Anastrozole is categorically contraindicated in women. Failure to comply with this recommendation may result in a failure of the hormonal system.
Side effects occur only as a result of individual intolerance or drug overdose. Consider that overdosing is difficult to notice, but if you stick to given doses, the risk of side effects is close to zero. If side effects suddenly occur, immediately stop taking the substance.
Main side effects:
- High blood pressure;
- Rash on the skin.
Also, the drug should not be used for people with impaired cardiovascular system.
Anastrozole in bodybuilding
Anastrozole and other drugs inhibiting the production of estrogen are actively used in bodybuilding with long courses of steroid hormones, as well as to reduce the “negative” effect of female sex hormones on the results of training. Not worth it once again to talk about the possible side effects of the use of drugs of this kind is not intended.
To understand the benefits of this drug, you need to try it on yourself. Most people praise anastrozole for its quick and powerful effect. Remember about the two-week reception and then you will not have to face the side effects of the drug.